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    • XTANDI

ENZALUTAMIDE (EN za LOO ta mide) treats prostate cancer. It works by blocking the effect of testosterone and other hormones in your body, which may slow or stop cancer cells from spreading or growing.


XTANDI Lifestyle Interactions

  • Enzalutamide 80mg, Oral tablet

    Interaction: Cannabis
    Severity: Major
    Notes for Consumers: Discuss cannabis use with your care team. The effects of cannabis may be altered if used with your medication.
    Notes for Professionals: Advise patients to avoid cannabis use during enzalutamide treatment. Concomitant use may decrease the concentration of some cannabinoids and alter their effects. The cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are CYP3A substrates and enzalutamide is a strong CYP3A inducer. Concomitant use of a cannabinoid product containing THC and CBD at an approximate 1:1 ratio with another strong CYP3A inducer decreased THC, 11-OH-THC, and CBD peak exposures by 36%, 87%, and 52% respectively.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.