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ENZALUTAMIDE (EN za LOO ta mide) treats prostate cancer. It works by blocking the effect of testosterone and other hormones in your body, which may slow or stop cancer cells from spreading or growing.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
This medication is not approved for use in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Artemether
-Certain antivirals for HIV or hepatitis, such as atazanavir, daclatasvir, doravirine, elbasvir, fostemsavir, grazoprevir, lopinavir, nelfinavir, paritaprevir, rilpivirine, ritonavir, tipranavir
-Certain medications for fungal infections, such as isavuconazonium, voriconazole
-Lonafarnib
-Lorlatinib
-Lurasidone
-Praziquantel
-Ranolazine
This medication may also interact with the following:
-Alfentanil
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin
-Clopidogrel
-Cyclosporine
-Ergot alkaloids, such as dihydroergotamine, ergotamine
-Fentanyl
-Gemfibrozil
-Midazolam
-Omeprazole
-Pimozide
-Quinidine
-Rifabutin
-Rifampin
-Rifapentine
-Sirolimus
-St. John's wort
-Tacrolimus
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your condition will be monitored carefully while you are receiving this medication.
Talk to your care team if you or your partner are pregnant or think either of you might be pregnant. This medication can cause serious birth defects. If your partner can get pregnant, use a condom during sex while taking this medication and for 3 months after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
-Increase in blood pressure
-Loss of balance or coordination
-Seizures
-Sudden and severe headache, confusion, change in vision, seizures, which may be signs of posterior reversible encephalopathy syndrome (PRES)
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Back pain
-Constipation
-Diarrhea
-Hot flashes
-Loss of appetite
-Unusual weakness or fatigue
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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