SPRAVATO

Esketamine 28mg, Nasal spray, solution

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake.

· Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants. Alcohol consumption may result in additive CNS depression.

Esketamine 28mg, Nasal spray, solution

Caffeine-containing Foods/Beverages

· Severity: Moderate

· Notes for Consumers: Before starting treatment with Esketamine, inform your doctor if you regularly consume caffeine-containing foods and beverages. Your doctor may advise you to limit your Caffeine intake. Both Esketamine and Caffeine can increase blood pressure. If you develop high blood pressure or experience symptoms of a very high blood pressure, such as chest pain or shortness of breath, contact your doctor right away.

· Notes for Professionals: Patients who regularly consume caffeine-containing foods or beverages may need to limit caffeine intake during esketamine treatment. Blood pressure should be closely monitored in patients treated with esketamine who regularly consume caffeine. Esketamine can increase blood pressure at all recommended doses and caffeine is a stimulant that may cause additive effects on blood pressure when combined with esketamine.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>