POLIVY
  • POLIVY

  • QTY 1 • 140 MG • VIAL • Near 77381

POLATUZUMAB VEDOTIN (poe la tooz ue mab ve doe tin) treats lymphoma. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

POLIVY Lifestyle Interactions

Polatuzumab Vedotin 140mg, Powder for solution for injection

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: Do not eat or drink Grapefruit or Grapefruit Juice while taking Polatuzumab Vedotin without talking to your health care provider. Grapefruit Juice or grapefruit-containing foods may increase side effects from Polatuzumab Vedotin.

· Notes for Professionals: Advise patients to avoid grapefruit juice while taking polatuzumab vedotin due to the risk of elevated exposure to the cytotoxic component of polatuzumab vedotin, MMAE. MMAE is metabolized by CYP3A4; grapefruit juice is a strong CYP3A4 inhibitor. Strong CYP3A4 inhibitors are predicted to increase the exposure of MMAE by 45%.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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