NERLYNX
  • NERLYNX

  • QTY 180 • 40 MG • Tablet • Near 77381

NERATINIB (ner A ti nib) treats breast cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

NERLYNX Lifestyle Interactions

Neratinib 40mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Avoid grapefruit and grapefruit juice during therapy with Neratinib. Side effects may get worse if you drink Grapefruit juice while taking Neratinib. Discuss any new or worsening side effects, such as diarrhea, nausea, abdominal pain, and fatigue, with your health care provider.

· Notes for Professionals: Have patients avoid grapefruit or grapefruit juice during neratinib treatment due to an increased risk of neratinib-related toxicity. Neratinib is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor increased neratinib exposure by 481%; concomitant use with other strong inhibitors of CYP3A4 may also increase neratinib concentrations.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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