LUPKYNIS
  • LUPKYNIS

  • QTY 180 • 7.9 MG • Capsule • Near 77381

VOCLOSPORIN (vok loe SPOR in) treats certain types of lupus. It works by slowing down an overactive immune system, which reduces inflammation and other symptoms of lupus.

LUPKYNIS Lifestyle Interactions

Voclosporin 7.9mg, Oral capsule

Grapefruit juice

· Severity: Severe

· Notes for Consumers: Do not take Grapefruit juice or grapefruit-containing foods and Voclosporin together. Taking these together may increase the risk of serious side effects.

· Notes for Professionals: Advise patients that the use of voclosporin and grapefruit juice is contraindicated; concomitant use may increase the exposure of voclosporin and the risk of voclosporin-related adverse effects such as nephrotoxicity, hypertension, and QT prolongation. Voclosporin is a sensitive CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor increased voclosporin exposure by approximately 19-fold.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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