Chlorpromazine Hydrochloride 25mg, Oral tablet
Enteral Feedings
· Severity: Major
· Notes for Consumers: Chlorpromazine oral concentrate must be diluted prior to administration. Do not mix it with nutritional supplement shakes or tube feedings such as Ensure or Pediasure. Mixing chlorpromazine oral concentrate with these products may lessen the drug's beneficial effect. You can continue to use these products, just separate the time you use them from the doses of the oral concentrate. Other alternatives should be used to dilute your dose. You may dilute chlorpromazine oral concentrate with tomato or fruit juice, milk, simple syrup, orange syrup, carbonated beverages, coffee, tea, or water. Semi-solid foods, such as applesauce or pudding, may also be used. If you are not sure if you are taking a nutritional supplement, ask your heatlh care professionals to review your medications and diet. Chlorpromazine tablets do not interact with these nutritional products.
· Notes for Professionals: Chlorpromazine oral concentrate appears to be physically incompatible with enteral feedings. This would include the dilution of the chlorpromazine concentrate in nutritional enteral supplements such as Ensure or Pediasure. These combinations are best avoided. If the patient is taking enteral feedings, separate the times of administration from the oral concentrate doses. Alternatives for dilution should be used. Chlorpromazine oral concentrate may be diluted with tomato or fruit juice, milk, simple syrup, orange syrup, carbonated beverages, coffee, tea, or water. Semi-solid foods, such as applesauce or pudding, may also be used. This interaction does not occur with other dosage forms, only the chlorpromazine oral concentrate.
Chlorpromazine Hydrochloride 25mg, Oral tablet
Cannabis
· Severity: Major
· Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
· Notes for Professionals: Advise patients to avoid cannabis use while taking CNS depressants due to the risk for additive CNS depression and potential for other cognitive adverse reactions.
Chlorpromazine Hydrochloride 25mg, Oral tablet
Alcohol
· Severity: Major
· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake.
· Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants. Alcohol consumption may result in additive CNS depression.
Chlorpromazine Hydrochloride 25mg, Oral tablet
Tobacco
· Severity: Major
· Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
· Notes for Professionals: Advise patients to avoid smoking tobacco while taking phenothiazines. Tobacco smoking may increase the clearance of phenothiazines, which may reduce their efficacy.