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ACETAMINOPHEN; CHLORPHENIRAMINE; DEXTROMETHORPHAN (a SEET a MIN oh fen; klor fen IR a meen; dex troe meth OR fan) treats the symptoms of the common cold, allergies, or flu. It works by reducing pain, fever, cough, and red, itchy eyes. It also decreases a runny or stuffy nose. It is a combination of acetaminophen, an antihistamine, and a cough suppressant.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with water. Take it as directed on the label. Use a specially marked oral syringe, spoon, or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food. Do not use it more often than directed.
Talk to your care team about the use of this medication in children. While it may be given to children as young as 12 years for selected conditions, precautions do apply.
People 65 years and older may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-MAOIs, such as Marplan, Nardil, and Parnate
This medication may also interact with the following:
-Alcohol
-Atropine
-Benzodiazepines, such as alprazolam, diazepam, lorazepam
-Certain medications for bladder problems, such as oxybutynin or tolterodine
-Certain medications for depression, such as amitriptyline or trazodone
-Certain medications for seizures, such as phenobarbital or primidone
-Certain medications for stomach problems, such as dicyclomine or hyoscyamine
-Certain medications for travel sickness, such as scopolamine
-Certain medications for Parkinson disease, such as benztropine or trihexyphenidyl
-Ipratropium
-Medications that cause drowsiness before a procedure, such as propofol
-Medications that help you fall asleep
-Medications that relax muscles
-Opioids for pain or cough
-Other antihistamines for allergy, cough, and cold
-Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
-St. John's wort
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. If you need to use this medication for more than 7 days, talk to your care team. Tell your care team if your fever lasts more than 3 days.
Do not take other medications that contain acetaminophen with this medication. Many non-prescription medications contain acetaminophen. Always read labels carefully. If you have questions, ask your care team.
If you take too much acetaminophen, get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.
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This does not apply. This medication is not for regular use. It should only be used as needed.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
-Trouble passing urine
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Confusion
-Constipation
-Dizziness
-Drowsiness
-Dry mouth
-Fatigue
-Headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, pour the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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