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ROLAPITANT (roe LA pi tant) prevents nausea and vomiting from chemotherapy. It works by blocking substances in your body that may cause nausea and vomiting. It belongs to a class of medications called antiemetics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Take it as directed on the prescription label. Usually, you will take it one hour before your chemotherapy begins. This medication may be taken with or without food. Do not take more often then directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of these:
-Pimozide
-Thioridazine
This medication may also interact with the following:
-Apalutamide
-Certain medications for blood pressure, heart disease, irregular heartbeat
-Certain medications for depression, anxiety, or mental health conditions
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin, fosphenytoin
-Certain medications that treat or prevent blood clots, such as warfarin and dabigatran
-Cyclosporine
-Dextromethorphan
-Digoxin
-Enzalutamide
-Irinotecan
-Methotrexate
-Opioid medications
-Rifampin
-Rifapentine
-Rosuvastatin
-Sirolimus
-Topotecan
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Do not take this medication if you already have nausea and vomiting. Ask your care team what to do if you already have nausea.
This medication should not be used continuously for a long time.
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If you miss a dose, take it as soon as you can. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Dizziness
-Hiccups
-Loss of appetite
-Stomach pain
-Upset stomach
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medications to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If your cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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