LOPERAMIDE (loe PER a mide) treats occasional diarrhea. It works by slowing down an overactive bowel, which decreases the number of bowel movements you have. It belongs to a group of medications called antidiarrheals. It is often used for a short period of time.

ULTRA A-D (Generic for IMODIUM A-D) Lifestyle Interactions

  • Loperamide Hydrochloride 2mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    • Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during loperamide treatment due to the risk of increased loperamide exposure and adverse reactions. Loperamide is a CYP3A and P-gp substrate and grapefruit juice is a strong CYP3A and P-gp inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.