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REMIFENTANIL (REM ee FEN ta nil) causes drowsiness before and during a procedure. It also treats pain. It works by blocking pain signals in the brain, so you do not feel pain or discomfort during the procedure. It belongs to a group of medications called opioids.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected or infused into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. While it may be given to children as young as newborns for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Naltrexone
-Olanzapine; samidorphan
-Safinamide
This medication may also interact with the following:
-Alcohol
-Benzodiazepines, such as alprazolam, diazepam, or lorazepam
-Buprenorphine
-Butorphanol
-Linezolid
-MAOIs, such as Marplan, Nardil, and Parnate
-Medications that cause drowsiness before a procedure, such as propofol
-Medications that help you fall asleep
-Medications that relax muscles
-Methylene blue
-Nalbuphine
-Other opioids
-Pentazocine
-Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
-Some antihistamines
-Some medications for depression, anxiety, or other mental health conditions
-Some medications for migraines, such as sumatriptan
-Some medications for nausea, such as dolasetron or ondansetron
-Some medications for nerve pain, such as gabapentin or pregabalin
-Some medications for seizures, such as phenobarbital or primidone
-Stimulant medications for ADHD, weight loss, or staying awake
-Supplements, such as St. John's wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your condition will be monitored carefully while you are receiving this medication. Tell your care team if your pain does not go away, gets worse, or if you have a new or different type of pain.
This medication can make you very drowsy because it slows down your brain and nervous system. Taking it with alcohol or other medications that also work this way can be dangerous. It can make it hard to breathe or stay awake. In serious cases, it can cause coma and death. Talk to your care team about all the medications, vitamins, and supplements you take. They can tell you what is safe to take together. Call emergency services right away if you have slow or shallow breathing, feel dizzy or confused, or have trouble staying awake.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells.
Talk to your care team if you may be pregnant. Prolonged use of this medication during pregnancy can cause temporary withdrawal in a newborn.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed. If you breastfeed while taking this medication, seek medical care right away if you notice the child has slow or noisy breathing, is unusually sleepy or not able to wake up, or is limp.
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This does not apply.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake
-Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Muscle stiffness
-Pain or trouble swallowing, heartburn, chest pain
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Dizziness
-Drowsiness
-Headache
-Itching
-Nausea
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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