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TRAMADOL HCL-ACETAMINOPHEN (Generic for ULTRACET)
- QTY 60
- 37.5-325MG
- Tablet
- Near 51502
TRAMADOL; ACETAMINOPHEN (TRA ma dol; a set a MEE noe fen) treats severe pain. It is often prescribed when other medications have not worked well enough or cannot be tolerated. It works by blocking pain signals in the brain. It is a combination of acetaminophen and an opioid.
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TRAMADOL HCL-ACETAMINOPHEN (Generic for ULTRACET)
- QTY 60
- 37.5-325MG
- Tablet
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TRAMADOL HCL-ACETAMINOPHEN (Generic for ULTRACET)
- QTY 60
- 37.5-325MG
- Tablet
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TRAMADOL HCL-ACETAMINOPHEN (Generic for ULTRACET) Lifestyle Interactions
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Tramadol Hydrochloride 37.5mg, Acetaminophen 325mg, Oral tablet
• Interaction: Alcohol• Severity: Major• Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk of liver injury. Contact your care team right away if you experience right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, or unusual weakness or fatigue.• Notes for Professionals: The risk of developing hepatotoxicity from acetaminophen appears to be increased in patients who regularly consume alcohol. Patients who drink more than 3 alcohol-containing drinks a day and take acetaminophen are at increased risk of developing hepatotoxicity. Acute or chronic alcohol use increases acetaminophen-induced hepatotoxicity by inducing CYP2E1 leading to increased formation of the hepatotoxic metabolite of acetaminophen. Also, chronic alcohol use can deplete liver glutathione stores. Administration of acetaminophen should be limited or avoided altogether in patients with alcoholism or patients who consume alcohol regularly. -
Tramadol Hydrochloride 37.5mg, Acetaminophen 325mg, Oral tablet
• Interaction: Cannabis• Severity: Major• Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.• Notes for Professionals: Advise patients to avoid cannabis use while taking CNS depressants due to the risk for additive CNS depression and potential for other cognitive adverse reactions. -
Tramadol Hydrochloride 37.5mg, Acetaminophen 325mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.• Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during tramadol treatment due to the risk of increased tramadol exposure and adverse reactions. Tramadol is a CYP2D6 and CYP3A substrate and grapefruit juice is a CYP2D6 and CYP3A inhibitor.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
