-
GRANISETRON (gra NI se tron) prevents nausea and vomiting from chemotherapy. It works by blocking substances in your body that may cause nausea and vomiting. It belongs to a class of medications called antiemetics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
-
This medication is for injection under the skin. It is given in a hospital or clinic setting.
A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
-
Do not take this medication with any of the following:
-Certain medications for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
-Cisapride
-Dronedarone
-Pimozide
-Thioridazine
This medication may also interact with the following:
-Certain medications for depression, anxiety, or psychotic disturbances
-Fentanyl
-Linezolid
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-Methylene blue (injected into a vein)
-Other medications that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone
-Phenobarbital
-Tramadol
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
-
This medication will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your care team.
-
It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
-
Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bowel blockage—stomach cramping, unable to have a bowel movement or pass gas, loss of appetite, vomiting
-Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome
-Skin infection—skin redness, swelling, warmth, or pain at the injection site
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Constipation
-Diarrhea
-Dizziness
-Fatigue
-Headache
-Pain, redness, irritation, or bruising at the injection site
-Stomach pain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
-
This medication is given in a hospital or clinic and will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
En Español
