• Image of Suboxone medication Image of Suboxone medication
    • BUPRENORPHINE-NALOXONE (Generic for SUBOXONE)

    • QTY 60
    • 8 MG-2 MG
    • FILM
    • Near  77381

BUPRENORPHINE; NALOXONE (byoo pre NOR feen; nal OX one) treats opioid use disorder. Buprenorphine works by reducing withdrawal symptoms and cravings to use opioids. Naloxone supports proper use of this medication. It is most effective when used in combination with counseling and behavior therapy.


BUPRENORPHINE-NALOXONE (Generic for SUBOXONE) Lifestyle Interactions

  • Buprenorphine Hydrochloride 8mg, Naloxone Hydrochloride 2mg, Oral Dissolving film

    Interaction: Alcohol
    Severity: Major
    Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake.
    Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants. Alcohol consumption may result in additive CNS depression.
  • Buprenorphine Hydrochloride 8mg, Naloxone Hydrochloride 2mg, Oral Dissolving film

    Interaction: Cannabis
    Severity: Major
    Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
    Notes for Professionals: Advise patients to avoid cannabis use while taking CNS depressants due to the risk for additive CNS depression and potential for other cognitive adverse reactions.
  • Buprenorphine Hydrochloride 8mg, Naloxone Hydrochloride 2mg, Oral Dissolving film

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during buprenorphine treatment due to the risk for increased buprenorphine exposure and adverse reactions. Buprenorphine is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.