• Image of SEGLENTIS medication Image of SEGLENTIS medication

    • SEGLENTIS

    • QTY 35
    • 44 MG-56MG
    • Tablet
    • Near  77381

CELECOXIB; TRAMADOL (sell a KOX ib; TRA ma dole) treats severe pain. It is prescribed when other pain medications have not worked or cannot be tolerated. It works by decreasing inflammation. It also blocks pain signals in the brain. It is a combination of an NSAID and an opioid.

SEGLENTIS Lifestyle Interactions

  • Celecoxib 56mg, Tramadol Hydrochloride 44mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    • Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during celecoxib treatment due to the risk of increased celecoxib exposure and adverse reactions. Celecoxib is a CYP2C9 substrate and grapefruit juice is a CYP2C9 inhibitor.

  • Celecoxib 56mg, Tramadol Hydrochloride 44mg, Oral tablet

    • Interaction: Alcohol
    • Severity: Major
    • Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk of stomach bleeding. Contact your care team right away if you experience bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds.
    • Notes for Professionals: Advise patients to avoid alcohol and alcohol-containing products while taking NSAIDs. Concomitant ingestion of alcohol with NSAIDs increases the risk of developing gastric irritation and GI mucosal bleeding. Alcohol is a mucosal irritant and NSAIDs decrease platelet aggregation. Routine ingestion of alcohol and NSAIDs can cause significant GI bleeding, which may or may not be overt. Even occasional concomitant use of NSAIDs and alcohol should be avoided. Chronic alcohol ingestion is often associated with hypoprothrombinemia and this condition increases the risk of bleeding.

  • Celecoxib 56mg, Tramadol Hydrochloride 44mg, Oral tablet

    • Interaction: Tobacco
    • Severity: Major
    • Notes for Consumers: Do not smoke or use tobacco products while taking this medication. Smoking while taking this medication increases the risk for stomach bleeding. Contact your care team right away if you experience bloody or black, tar-like stools, or vomiting blood or brown material that looks like coffee grounds.
    • Notes for Professionals: Advise patients to avoid smoking tobacco while taking nonsteroidal anti-inflammatory drugs (NSAIDs). Concomitant use of NSAIDs with tobacco smoking may enhance the risk of gastrointestinal side effects, including peptic ulcer and GI bleeding. Patients using tobacco and NSAIDs concurrently should be monitored closely for GI adverse reactions.

  • Celecoxib 56mg, Tramadol Hydrochloride 44mg, Oral tablet

    • Interaction: Cannabis
    • Severity: Major
    • Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
    • Notes for Professionals: Advise patients to avoid cannabis use while taking CNS depressants due to the risk for additive CNS depression and potential for other cognitive adverse reactions.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.