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    • SAXAGLIPTIN-METFORMIN ER (Generic for KOMBIGLYZE XR)

    • QTY 30
    • 2.5-1000MG
    • TBMP 24HR
    • Near  77381

SAXAGLIPTIN; METFORMIN (SAX a glip tin; met FOR min) treats type 2 diabetes. It works by decreasing your blood sugar (glucose). Changes to diet and exercise are often combined with this medication.


SAXAGLIPTIN-METFORMIN ER (Generic for KOMBIGLYZE XR) Lifestyle Interactions

  • Saxagliptin 2.5mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

    Interaction: Alcohol
    Severity: Major
    Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk for dangerously high lactic acid levels. Call emergency services right away if you experience muscle pain or cramps, stomach pain, trouble breathing, or general discomfort and fatigue.
    Notes for Professionals: Patients taking metformin should be advised to avoid alcohol use. Blood lactate concentrations and the lactate to pyruvate ratio are increased during excessive (acute or chronic) intake of alcohol with metformin.
  • Saxagliptin 2.5mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

    Interaction: Grapefruit juice
    Severity: Mild
    Notes for Consumers: Saxagliptin and grapefruit juice may be taken together. Tell your healthcare professional about any unusual symptom that occurs.
    Notes for Professionals: Saxagliptin plasma concentrations are expected to increase in the presence of moderate CYP 3A4/5 inhibitors such as grapefruit juice, but saxagliptin dose adjustment is not advised.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.