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MEDROXYPROGESTERONE (me DROX ee proe JES te rone) treats irregular menstrual cycles. It may also be used to prevent the lining of the uterus from becoming too thick in people taking estrogen after menopause. It works by increasing levels of the hormone progestin in the body. This medication is a progestin hormone.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medication more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed. While this medication may be prescribed for children as young as 13 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Barbiturate medications for inducing sleep or treating seizures
-Bosentan
-Carbamazepine
-Phenytoin
-Rifampin
-St. John's Wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress.
You will need pelvic exams, breast exams, and mammograms on a regular schedule while you are taking this medication.
Stop taking this medication and talk to your care team right away if you may be pregnant. Taking it before you know you are pregnant is not likely to cause fetal side effects.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
-Breast tissue changes, new lumps, redness, pain, or discharge from the nipple
-Gallbladder problems—severe stomach pain, nausea, vomiting, fever
-Increase in blood pressure
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
-Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
-Unusual vaginal discharge, itching, or odor
-Vaginal bleeding after menopause, pelvic pain
-Worsening mood, feelings of depression
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Breast pain or tenderness
-Change in sex drive or performance
-Headache
-Irregular menstrual cycles or spotting
-Nausea
-Weight gain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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