• Image of Talwin Nx medication Image of Talwin Nx medication

    • PENTAZOCINE-NALOXONE HCL

PENTAZOCINE; NALOXONE (pen TAZ oh seen; nal OX one) treats severe pain. It is often prescribed when other medications have not worked well enough or cannot be tolerated. Pentazocine works by blocking pain signals in the brain. Naloxone supports proper use of this medication. It belongs to a group of medications called opioids.

PENTAZOCINE-NALOXONE HCL Lifestyle Interactions

  • Naloxone Hydrochloride 0.5mg, Pentazocine Hydrochloride 50mg, Oral tablet

    • Interaction: Cannabis
    • Severity: Major
    • Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis. Call emergency services right away if you experience slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, or trouble staying awake.
    • Notes for Professionals: Advise patients to avoid cannabis use while taking CNS depressants due to the risk for additive CNS depression and potential for other cognitive adverse reactions.

  • Naloxone Hydrochloride 0.5mg, Pentazocine Hydrochloride 50mg, Oral tablet

    • Interaction: Alcohol
    • Severity: Major
    • Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake.
    • Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants. Alcohol consumption may result in additive CNS depression.

  • Naloxone Hydrochloride 0.5mg, Pentazocine Hydrochloride 50mg, Oral tablet

    • Interaction: Tobacco
    • Severity: Major
    • Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
    • Notes for Professionals: Advise patients to avoid smoking tobacco while taking pentazocine. People who smoke have been observed to metabolize 40% more pentazocine than non-smokers. Enhanced metabolic clearance may reduce pentazocine efficacy.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.