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    • OGSIVEO

NIROGACESTAT (NYE roe GAY se stat) treats desmoid tumors, growths that occur in connective tissues, such as fat, muscle, and blood vessels. It works by slowing or stopping the growth of tumor cells.


OGSIVEO Lifestyle Interactions

  • Nirogacestat 50mg, Oral tablet

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during nirogacestat treatment due to the risk of increased nirogacestat exposure and adverse reactions. Nirogacestat is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.