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OBETICHOLIC ACID (oh BET i KOE lik AS id) treats primary biliary cholangitis (PBC), a condition that causes injury to the bile ducts in your liver. It works by preventing the buildup of bile in your liver. This delays worsening symptoms.
Obeticholic acid 5mg, Oral tablet
Caffeine-containing Foods/Beverages
· Severity: Moderate
· Notes for Consumers: Although an interaction is possible, these drugs are often used together. Side effects from Caffeine may get worse if you take these drugs together. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. You may need to limit your Caffeine intake. Common foods and beverages containing caffeine include coffee, teas, colas and chocolate. Many non-prescription drugs and diet aids may also contain caffeine.
· Notes for Professionals: Obeticholic acid may increase the exposure to concomitant drugs that are CYP1A2 substrates, such as caffeine. Concomitant administration of 200 mg caffeine as a single dose with obeticholic acid 10 mg once daily resulted in a 42% increase in caffeine AUC and a 6% increase in caffeine Cmax. Therapeutic monitoring is recommended with coadministration. No specific management is recommended except in patients who complain of caffeine-related side effects like nausea, tremor, or palpitations. In such patients, the dosage of caffeine-containing medications or the ingestion of caffeine-containing products may need to be reduced.
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Number of Uses:
ocaliva
5 MG | Tablet | 30 tablets
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