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NIFEDIPINE (nye FED i peen) treats high blood pressure. It works by relaxing blood vessels, which decreases the amount of work the heart has to do. It belongs to a group of medications called calcium channel blockers.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medication. Swallow the tablets whole. Some tablets need to be taken on an empty stomach. Ask your pharmacist or care team if you have any questions. Keep taking it unless your care team tells you to stop.
Do not take this medication with grapefruit juice.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Certain medications for seizures like carbamazepine, phenobarbital, phenytoin
-Lumacaftor; ivacaftor
-Rifabutin
-Rifampin
-Rifapentine
-St. John's Wort
This medication may also interact with the following:
-Antiviral medications for HIV or AIDS
-Certain medications for blood pressure
-Certain medications for diabetes
-Certain medications for erectile dysfunction
-Certain medications for fungal infections like ketoconazole, fluconazole, and itraconazole
-Certain medications for irregular heart beat like flecainide and quinidine
-Certain medications that treat or prevent blood clots like warfarin
-Clarithromycin
-Digoxin
-Dolasetron
-Erythromycin
-Fluoxetine
-Grapefruit juice
-Local or general anesthetics
-Nefazodone
-Orlistat
-Quinupristin; dalfopristin
-Sirolimus
-Stomach acid blockers like cimetidine, ranitidine, omeprazole, or pantoprazole
-Tacrolimus
-Valproic acid
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Check your blood pressure as directed. Ask your care team what your blood pressure should be. Also, find out when you should contact them.
Do not treat yourself for coughs, colds, or pain while you are using this medication without asking your care team for advice. Some medications may increase your blood pressure.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand up or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
The tablet shell for some brands of this medication does not dissolve. This is normal. The tablet shell may appear whole in the stool. This is not a cause for concern.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
-Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Worsening chest pain (angina)—pain, pressure, or tightness in the chest, neck, back, or arms
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Constipation
-Dizziness
-Facial flushing, redness
-Headache
-Heart palpitations—rapid, pounding, or irregular heartbeat
-Nausea
-Stomach pain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Keep the container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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