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MONOJECT SAFETY SYR TIP CAP
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MONOJECT SAFETY SYR TIP CAP Lifestyle Interactions
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Lidocaine Hydrochloride 0.5%, Epinephrine 1:200,000, Solution for injection
• Interaction: Cannabis• Severity: Major• Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis.• Notes for Professionals: Advise patients to avoid cannabis use during lidocaine treatment due to decreased exposure of lidocaine which may alter its efficacy. Cannabis use induces CYP1A2 and lidocaine is a CYP1A2 substrate. The induction potential of cannabis is greatest with chronic inhalation. Other routes of administration or sporadic use may have less of an effect. -
Lidocaine Hydrochloride 0.5%, Epinephrine 1:200,000, Solution for injection
• Interaction: Caffeine-containing Foods/Beverages• Severity: Moderate• Notes for Consumers: Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Epinephrine and avoid medicines containing additional Caffeine whenever possible. Taking a high amount of Caffeine with Epinephrine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.• Notes for Professionals: Caffeine is a CNS-stimulant and such actions are expected to be additive when coadministered with other CNS stimulants or psychostimulants.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.