RUXOLITINIB (RUX oh LI ti nib) treats blood and bone marrow cancers. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells. It may also be used to treat a condition that can occur after a stem cell or bone marrow transplant (graft versus host disease).

JAKAFI XR Lifestyle Interactions

  • Ruxolitinib 11mg, Oral tablet, extended release

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not drink grapefruit juice or eat grapefruit or grapefruit-containing foods while taking Ruxolitinib. Side effects from Ruxolitinib may get worse. Contact your prescriber immediately if you experience any new or unusual side effects.
    • Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during ruxolitinib treatment due to the risk of increased ruxolitinib exposure and adverse reactions. Ruxolitinib is a CYP3A substrate and grapefruit juice is a strong CYP3A inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.