ISOVUE-M 300 Lifestyle Interactions

Iopamidol 612mg/1mL, Solution for injection

Caffeine-containing Foods/Beverages

· Severity: Major

· Notes for Consumers: Although Radiopaque Contrast Agents and Caffeine can interact, Radiopaque Contrast Agents are only used in a hospital or clinic during various imaging procedures. Sometimes, Radiopaque Contrast Agents (examples iohexol or Omnipaque or Iopamidol or Isovue) are injected into your spinal fluid through your back (called intrathecally). If you have a high intake of caffeinated beverages (like coffee, colas, or teas) and you receive Radiopaque Contrast Agents through your back, the risk of seizures could be increased. Discuss your caffeine intake with your health care provider prior to any procedures or exams.

· Notes for Professionals: Use of medications that lower the seizure threshold should be carefully evaluated when considering intrathecal radiopaque contrast agents. Caffeine and caffeine containing products should be discontinued at least 48 hours before myelography and should not be resumed for at least 24 hours postprocedure.

Iopamidol 612mg/1mL, Solution for injection

Alcohol

· Severity: Moderate

· Notes for Consumers: Although Radiopaque Contrast Agents and Ethanol (alcoholic beverages) can interact, Radiopaque Contrast Agents (examples Iohexol or Omnipaque and Iopamidol or Isovue) are only used in a hospital or clinic during various imaging procedures. Sometimes, Contrast Agents are injected into your spinal fluid through your back (called intrathecally). If you drink alcoholic beverages on a regular basis, you could be at increased risk for seizures if a Contrast Agent is given through your back. If you frequently drink alcoholic beverages, discuss the use of Contrast Agents with your health care provider before any exams or procedures.

· Notes for Professionals: Ethanol abuse or abrupt discontinuation of chronic ethanol use has been associated with seizures and fatalities; intrathecal radiopaque contrast agents should be administered cautiously in patients who chronically abuse alcohol.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

DISCLAIMER: This content is provided for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.

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