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IBUPROFEN LYSINE (eye BYOO proe fen LAHY seen) treats a heart defect called patent ductus arteriosus (PDA), an opening between blood vessels near the heart in newborn infants. It works by closing the PDA. It belongs to a group of medications called NSAIDs.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is for infusion into a vein. It is given in a hospital.
This medication is specifically for use in newborns.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Aspirin and aspirin-like medications
-Certain antibiotics
-Digoxin
-Diuretics
-Medications that treat or prevent blood clots such as warfarin
-NSAIDs, medications for pain and inflammation, such as ibuprofen or naproxen
-Steroid medications such as prednisone or cortisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your baby's condition will be watched closely while this treatment is given. Your baby will also receive regular blood tests and exams. Talk with your care team if you have any concerns.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your healthcare provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
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This does not apply.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
-Bleeding in the brain—severe headache, stiff neck, confusion, dizziness, change in vision, numbness or weakness of the face, arm, or leg, trouble speaking, trouble walking, vomiting
-Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
-Rash, fever, and swollen lymph nodes
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Round red or dark patches on the skin that may itch, burn, and blister
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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