Nutritional Supplement

Thymus Extracts

  • Allergy and Lung Support

    Allergies and Sensitivities

    Thymomodulin, a special preparation of the thymus gland of calves, has been shown to prevent allergic reactions to food in a double-blind study of allergic children.
    Allergies and Sensitivities
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    Thymomodulin is a special preparation of the thymus gland of calves. In a double-blind study of allergic children who had successfully completed an elimination diet, 120 mg per day of thymomodulin prevented allergic skin reactions to food and lowered blood levels of antibodies associated with those foods.1 These results confirmed similar findings in an earlier, controlled trial.2

    Hay Fever

    A thymus extract known as Thymomodulin has been shown in studies to improve the symptoms of hay fever and allergic rhinitis.
    Hay Fever
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    The oral administration of a thymus extract known as Thymomodulin has been shown in preliminary studies and double-blind trials to improve the symptoms of hay fever and allergic rhinitis.3,4,5 Presumably this clinical improvement is the result of restoration of proper control over immune function.

    Asthma

    A thymus extract known as thymomodulin has been shown to improve the symptoms and course of asthma, presumably as the result of restoration of proper immune function control.
    Asthma
    ×
     

    The oral administration of a thymus extract known as thymomodulin has been shown in preliminary and double-blind clinical trials to improve the symptoms and course of asthma.6,7,8,9 Presumably this clinical improvement is the result of restoration of proper control over immune function.

  • Immune System Support

    Bronchitis

    Thymus extract from calves, known as Thymomodulin, has been found to decrease the frequency of respiratory infections in children who were prone to such infections.
    Bronchitis
    ×
     

    The thymus gland plays a number of important roles in the functioning of the immune system. Thymus extract from calves, known as Thymomodulin®, has been found, in a double-blind study, to decrease the frequency of respiratory infections in children who were prone to such infections.10 The amount of Thymomodulin used in that study was 3 mg per kg of body weight per day.

    Immune Function

    The thymus gland is responsible for many immune system functions. A thymus extract known as Thymomodulin has been shown to improve immune function in some people.
    Immune Function
    ×
    The thymus gland is responsible for many immune system functions. Preliminary studies suggest that a thymus extract known as Thymomodulin® may improve immune function, and double-blind trials in children and adults with a history of recurrent respiratory-tract infections have found reduced numbers of recurrent infections with Thymomodulin supplementation.11,12,13,14,15 Thymomodulin has also been shown in a double-blind study to improve immune function in cases of exercise-induced immune suppression, and in preliminary studies to improve immune function in people with diabetes and in elderly people.16,17,18,19

    HIV and AIDS Support

    In one trial, a thymus extract known as Thymomodulin improved several immune parameters among people with early HIV infection, including an increase in T-helper cells.
    HIV and AIDS Support
    ×
     

    In a preliminary trial, a thymus extract known as Thymomodulin improved several immune parameters among people with early HIV infection, including an increase in the number of T-helper cells.20

What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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References

1. Cavagni G, Piscopo E, Rigoli E, et al. Food allergy in children: an attempt to improve the effects of the elimination diet with an immunomodulating agent (thymomodulin). A double-blind clinical trial. Immunopharmacol Immunotoxicol 1989;11:131-42.

2. Genova R, Guerra A. Thymomodulin in management of food allergy in children. Int J Tissue React 1986;8:239-42.

3. Cazzola P, Mazzanti P, Bossi G. In vivo modulating effect of a calf thymus acid lysate on human T lymphocyte subsets and CD4+/CD8+ ratio in the course of different diseases. Curr Ther Res 1987;42:1011-7.

4. Kouttab NM, Prada M, Cazzola P. Thymomodulin: Biological properties and clinical applications. Med Oncol Tumor Pharmacother 1989;6:5-9 [review].

5. Marzari R, Mazzanti P, Cazzola P, Pirodda E. Perennial allergic rhinitis: prevention of the acute episodes with Thymomodulin. Minerva Med 1987;78:1675-81.

6. Cazzola P, Mazzanti P, Bossi G. In vivo modulating effect of a calf thymus acid lysate on human T lymphocyte subsets and CD4+/CD8+ ratio in the course of different diseases. Curr Ther Res 1987;42:1011-7.

7. Kouttab NM, Prada M, Cazzola P. Thymomodulin: Biological properties and clinical applications. Med Oncol Tumor Pharmacother 1989;6:5-9 [review].

8. Genova R, Guerra A. A thymus extract (thymomodulin) in the prevention of childhood asthma. Pediatr Med Chir 1983;5:395-402.

9. Bagnato A, Brovedani P, Comina P, et al. Long-term treatment with thymomodulin reduces airway hyperresponsiveness to methacholine. Ann Allergy 1989;62:425-8.

10. Fiocchi A, Borella E, Riva E, et al. Double-blind clinical trial for the evaluation of the therapeutical effectiveness of a calf thymus derivative (Thymomodulin) in children with recurrent respiratory infections. Thymus 1986;8:331-9.

11. Fiocchi A, Borella E, Riva E, et al. Double-blind clinical trial for the evaluation of the therapeutical effectiveness of a calf thymus derivative (Thymomodulin) in children with recurrent respiratory infections. Thymus 1986;8:331-9.

12. Galli L, de Martino M, Azzari C, et al. Preventive effect of thymomodulin in recurrent respiratory infections in children. Pediatr Med Chir 1990;12:229-32.

13. Vettori G, Lazzaro A, Mazzanti P, Cazzola P. Prevention of recurrent respiratory infections in adults. Minerva Med 1987;78:1281-9.

14. Longo F, Lepore L, Agosti E, Panizon F. Evaluation of the effectiveness of thymomodulin in children with recurrent respiratory infections. Pediatr Med Chir 1988;10:603-7.

15. Maiorano V, Chianese R, Fumarulo R, et al. Thymomodulin increases the depressed production of superoxide anion by alveolar macrophages in patients with chronic bronchitis. Int J Tissue React 1989;11:21-5.

16. Garagiola U, Buzzetti M, Cardella E. Immunological patterns during regular intensive training in athletes: quantification and evaluation of a preventive pharmacological approach. J Int Med Res 1995;23:85-95.

17. Wysocki J, Wierusz-Wysocka B, Wykretowicz A, Wysocki H. The influence of thymus extracts on the chemotaxis of polymorphonuclear neutrophils (PMN) from patients with insulin-dependent diabetes mellitus (IDD). Thymus 1992;20:63-7.

18. Calsini P, Mocchegiani E, Fabris N. The pharmacodynamics of thymomodulin in elderly humans. Drugs Exp Clin Res 1985;11:671-4.

19. Braga PC, Dal Sasso M, Maci S, et al. Restoration of polymorphonuclear leukocyte function in elderly subjects by thymomodulin. J Chemother 1994;6:354-9.

20. Valesini G, Barnaba V, Benvenuto R, et al. A calf thymus lysate improves clinical symptoms and T-cell defects in the early stages of HIV infection: Second report. Eur J Cancer Clin Oncol 1987;23:1915-9.

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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Medication journal & mood log

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