Nutritional Supplement

Peony

  • Women's Health

    Dysmenorrhea

    An herbal formulation known as toki-shakuyaku-san combines peony root with other herbs and has been found to reduce cramping and pain associated with dysmenorrhea.
    Dysmenorrhea
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    Dong quai has been used either alone or in combination with other Traditional Chinese Medicine herbs to help relieve painful menstrual cramps. Many women take 3–4 grams per day. A Japanese herbal formulation known as toki-shakuyaku-san combines peony root (Paeonia spp.) with dong quai and four other herbs and has been found to effectively reduce symptoms of cramping and pain associated with dysmenorrhea.17

    Premenstrual Syndrome

    In Traditional Chinese medicine, dong quai is used in combination with herbs such as peony and osha for menopausal symptoms and menstrual cramps.
    Premenstrual Syndrome
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    In Traditional Chinese Medicine, dong quai is rarely used alone and is typically used in combination with herbs such as peony (Paeonia officinalis) and osha (Ligusticum porteri) for menopausal symptoms as well as for menstrual cramps.18 However, no clinical trials have been completed to determine the effectiveness of dong quai for PMS.

    Polycystic Ovary Syndrome

    Peony shows some weak estrogen-like effects, and, particularly as part of the formula shakuyaku-kanzo-to, preliminary research suggests it may improve fertility in women affected by polycystic ovary syndrome.
    Polycystic Ovary Syndrome
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    Peony shows some weak estrogen-like effects, acting like a very weak anti-estrogen, particularly as part of the formula shakuyaku-kanzo-to. In a preliminary study, this formula was shown to improve fertility in women affected by polycystic ovary syndrome.19
  • Menstrual and PMS Support

    Dysmenorrhea

    An herbal formulation known as toki-shakuyaku-san combines peony root with other herbs and has been found to reduce cramping and pain associated with dysmenorrhea.
    Dysmenorrhea
    ×
     

    Dong quai has been used either alone or in combination with other Traditional Chinese Medicine herbs to help relieve painful menstrual cramps. Many women take 3–4 grams per day. A Japanese herbal formulation known as toki-shakuyaku-san combines peony root (Paeonia spp.) with dong quai and four other herbs and has been found to effectively reduce symptoms of cramping and pain associated with dysmenorrhea.20

    Premenstrual Syndrome

    In Traditional Chinese medicine, dong quai is used in combination with herbs such as peony and osha for menopausal symptoms and menstrual cramps.
    Premenstrual Syndrome
    ×
     

    In Traditional Chinese Medicine, dong quai is rarely used alone and is typically used in combination with herbs such as peony (Paeonia officinalis) and osha (Ligusticum porteri) for menopausal symptoms as well as for menstrual cramps.21 However, no clinical trials have been completed to determine the effectiveness of dong quai for PMS.

  • Heart and Circulatory Health

    Atherosclerosis

    Peony has been shown to prevent platelet aggregation.
    Atherosclerosis
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    Turmeric’s active compound curcumin has shown potent anti-platelet activity in animal studies.22 It has also demonstrated this effect in preliminary human studies.23 In a similar vein, bilberry has been shown to prevent platelet aggregation24 as has peony.25 However, none of these three herbs has been documented to help atherosclerosis in human trials.

  • Allergy and Lung Support

    Hay Fever

    The Japanese herbal formula known as sho-seiryu-to has been shown to reduce symptoms, such as sneezing, for people with hay fever.
    Hay Fever
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    The Japanese herbal formula known as sho-seiryu-to has been shown to reduce symptom, such as sneezing, for people with hay fever.26 Sho-seiryu-to contains licorice, cassia bark, schisandra, ma huang, ginger, peony root, pinellia, and asiasarum root.

  • Immune System Support

    HIV and AIDS Support

    The herbal formula sho-saiko-to has been shown to have beneficial immune effects on white blood cells in people infected with HIV.
    HIV and AIDS Support
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    The Chinese herb bupleurum, as part of the herbal formula sho-saiko-to, has been shown to have beneficial immune effects on white blood cells taken from people infected with HIV.27 Sho-saiko-to has also been shown to improve the efficacy of the anti-HIV drug lamivudine in the test tube.28 One preliminary study found that 7 of 13 people with HIV given sho-saiko-to had improvements in immune function.29 Double-blind trials are needed to determine whether bupleurum or sho-saiko-to might benefit people with HIV infection or AIDS. Other herbs in sho-saiko-to have also been shown to have anti-HIV activity in the test tube, most notably Asian scullcap.30 Therefore studies on sho-saiko-to cannot be taken to mean that bupleurum is the only active herb involved. The other ingredients are peony root, pinellia root, cassia bark, ginger root, jujube fruit, Asian ginseng root, Asian scullcap root, and licorice root.

    Fever

    Fever
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What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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Traditional Use (May Not Be Supported by Scientific Studies)

Peony is an ancient, traditional Chinese herbal medicine.31 The plant was and is extensively cultivated as an ornamental plant as well. Peony is named for the mythical Greek figure Paeon, who was said to be a student of Aesculapius, the great physician.31 Paeon used the peony plant (various species also grow in Europe) to heal a wound for the god Pluto. This earned Aesculapius’s jealous wrath, but Pluto saved Paeon from death by turning him into a peony plant.

Bai shao or white peony was considered useful for hypertension, chest pain, muscle cramping and spasms, and fever.31 It was an important remedy for female reproductive conditions ranging from dysmenorrhea (painful menstruation) to irregular menses.34 Chi shao or red peony was used for bleeding or lack of blood movement, depending on how it was prepared.35 Moutan was also considered helpful for problems characterized by bleeding, such as nosebleeds, bleeding wounds, or menorrhagia (excessive menstrual bleeding).36

References

1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Newton, MA: Integrative Medicine Communications, 1998, 364.

2. Yamashita JI. Effect of Tsumura skakuyaku-kanzo-to on pain at muscle twitch during and after dialysis in the patients undergoing dialysis. Pain and Kampo Medicine 1992;2:18-20.

3. Kotani N, Oyama T, Hashimoto H, et al. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea—a double-blind study. Am J Chin Med 1997;25:205-12.

4. Ohta H, Ni JW, Matsumoto K, et al. Paeony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. Pharmacol Biochem Behav 1993;45:719-23.

5. Okubo T, Nagai F, Seto T, et al. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. Biol Pharm Bull 2000;23:199-203.

6. Tomoda M, Matsumoto K, Shimizu N, et al. Characterization of a neutral and an acidic polysaccharide having immunological activities from the root of Paeonia lactiflora. Biol Pharm Bull 1993;16:1207-10.

7. Tomoda M, Matsumoto K, Shimizu N, et al. An acidic polysaccharide with immunological activities from the root of Paeonia lactiflora. Biol Pharm Bull 1994;17:1161-4.

8. Qi XG. Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage. Chung Hsi I Chieh Ho Tsa Chih 1991;11:69, 102-4 [in Chinese].

9. Yang DG. Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1994;14:195, 207-9 [in Chinese].

10. Wang CB, Chang AM. Plasma thromboxane B2 changes in severe icteric hepatitis treated by traditional Chinese medicine—dispelling the pathogenic heat from blood, promoting blood circulation and administrating large doses of radix Paeoniae—a report of 6 cases. Chung Hsi I Chieh Ho Tsa Chih 1985;5:326-8, 322 [in Chinese].

11. Wang Y, Ma R. Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes. Chung Hsi I Chieh Ho Tsa Chih 1990;10:70, 101-2 [in Chinese].

12. Xue JX, Jiang Y, Yan YQ. Effects of the combination of Astragalus membranaceus (Fisch.) Bge. (AM), root of Angelica sinensis (Oliv.) Diels. (TAS), Cyperus rotundus L. (CR), Ligusticum chuanxiong Hort. (LC) and Paeonia veitchii Lynch (PV) on the hemorrheological changes in normal rats. Chung Kuo Chung Yao Tsa Chih 1993;18:621-3, 640 [in Chinese].

13. Zhang Y. The effects of nifedipine, diltiazem, and Paeonia lactiflora Pall. on atherogenesis in rabbits. Chung Hua Hsin Hsueh Kuan Ping Tsa Chih 1991;19:100-3 [in Chinese].

14. Liu J. Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis. Chung Hua I Hsueh Tsa Chih (Chin Med J) 1983;63:477-81 [in Chinese].

15. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica, rev ed. Seattle: Eastland Press, 1993:70-1.

16. Takahashi K, Kitao M. Effect of TJ-68 (shakuyaku-kanzo-to) on polycystic ovarian disease. Int J Fertil Menopausal Stud 1994;39:69-76.

17. Kotani N, Oyama T, Hashimoto H, et al. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea—a double-blind study. Am J Chin Med 1997;25:205-12.

18. Qi-bing M, Jing-yi T, Bo C. Advance in the pharmacological studies of radix Angelica sinensis (oliv) diels (Chinese danggui). Chin Med J 1991;104:776-81.

19. Takahashi K, Kitao M. Effect of TJ-68 (shakuyaku-kanzo-to) on polycystic ovarian disease. Int J Fertil Menopausal Stud 1994;39:69-76.

20. Kotani N, Oyama T, Hashimoto H, et al. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea—a double-blind study. Am J Chin Med 1997;25:205-12.

21. Qi-bing M, Jing-yi T, Bo C. Advance in the pharmacological studies of radix Angelica sinensis (oliv) diels (Chinese danggui). Chin Med J 1991;104:776-81.

22. Srivastava R, Dikshit M, Srimal RC, Dhawan BN. Anti-thrombotic effect of curcumin. Thromb Res 1985;40:413-7.

23. Srivastava KC, Bordia A, Verma SK. Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. Prost Leuk Essen Fat Acids. 1995;52:223-7.

24. Pulliero G, Montin S, et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus (bilberry) anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.

25. Liu J. Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis. Chin Med J 1983;63:477-81 [in Chinese].

26. Baba S, Takasaka T. Double-blind clinical trial of sho-seiryu-to (TJ-19) for perennial nasal allergy. Clin Otolaryngol 1995;88:389-405.

27. Inada Y, Watanabe K, Kamiyama M, et al. In vitro immunomodulatory effects of traditional Kampo medicine (sho-saiko-to: SST) on peripheral mononuclear cells in patients with AIDS. Biomed Pharmacother 1990;44:17-9.

28. Piras G, Makino M, Baba M. Sho-saiko-to, a traditional kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol 1997;41:835-9.

29. Fujimaki M, Hada M, Ikematsu S, et al. Clinical efficacy of two kinds of kampo medicine on HIV infected patients. Int Conf AIDS 1989;5:400 [abstract no. W.B.P.292].

30. Li BQ, Fu T, Yan YD, et al. Inhibition of HIV infection by baicalin—a flavonoid compound purified from Chinese herbal medicine. Cell Mol Biol Res 1993;39:119-24.

31. Foster S, Yue CX. Herbal Emissaries: Bringing Chinese Herbs to the West. Rochester, VT: Healing Arts Press, 1992:200-7.

32. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica, rev ed, Seattle: Eastland Press, 1993:331-2.

33. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica, rev ed, Seattle: Eastland Press, 1993:277-8.

34. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica, rev ed, Seattle: Eastland Press, 1993:70-1.

35. Foster S, Yue CX. Herbal Emissaries: Bringing Chinese Herbs to the West. Rochester, VT: Healing Arts Press, 1992:200-7.

36. Takahashi K, Kitao M. Effect of TJ-68 (shakuyaku-kanzo-to) on polycystic ovarian disease. Int J Fertil Menopausal Stud 1994;39:69-76.

37. Guo TL, Zhou XW. Clinical observations on the treatment of the gestational hypertension syndrome with angelica and paeonia powder. Chung Hsi I Chieh Ho Tsa Chih 1986;6:714-6, 707 [in Chinese].

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

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