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Health Condition

Fibrocystic Breast Disease

About This Condition

Fibrocystic breast disease (FBD) is a term given to a very common group of benign conditions affecting the breast in younger women.

Symptoms

Both breasts become tender or painful and lumpy, and these symptoms vary at different times in the menstrual cycle. Despite the fact that signs and symptoms of FBD appear to be quite distinct from textbook signs and symptoms of breast cancer, any lump in the breast should be diagnosed by a doctor to rule out the possibility of cancer.

Other Therapies

All women, including those with FBD, are encouraged to examine their breasts monthly and have regular medical evaluations, including mammograms after the age of 50.

References

1. Mansel RE, Pye JK, Hughes LE. Effects of Essential fatty acids on cyclical mastalgia and noncyclical breast disorders. In Omega-6 essential fatty acids: Pathophysiology and roles in clinical medicine. New York: Alan R Liss, 1990, 557-66.

2. Preece PE, Hanslip JI, Gilbert L, et al. Evening primrose oil (EFAMOL) for mastalgia. In: Clinical Uses of Essential Fatty Acids, ed. DF Horrobin, Montreal: Eden Press, 1982, 147-54.

3. Mansel RE, Harrison BJ, Melhuish J, et al. A randomized trial of dietary intervention with essential fatty acids in patients with categorized cysts. Ann NY Acad Sci 1990;586:288-94.

4. Gateley CA, Maddox PR, Pritchard GA, et al. Plasma fatty acid profiles in benign breast disorders. Br J Surg 1992;79:407-9.

5. Harding C, Harvey J, Kirkman R, Bundred N. Hormone replacement therapy-induced mastalgia responds to evening primrose oil. Br J Surg 1996;83(Suppl 1):24 [abstract # Breast 012].

6. Pye JK, Mansel RE, Hughes LE. Clinical experience of drug treatments for mastalgia. Lancet 1985;ii:373-7.

7. Halaška M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing Vitex agnus extract: results of a placebo-controlled double-blind study. The Breast 1999;8:175-81.

8. Böhnert KJ. The use of Vitex agnus castus for hyperprolactinemia. Quart Rev Nat Med 1997;Spring:19-21.

9. Krouse TB, Eskin BA, Mobini J. Age-related changes resembling fibrocystic disease in iodine-blocked rat breasts. Arch Pathol Lab Med 1979;103:631-4.

10. Ghent WR, Eskin BA, Low DA, Hill L. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.

11. Abrams AA. Use of vitamin E in chronic cystic mastitis. N Engl J Med 1965;272(20):1080-1.

12. London RS, Sundaram GS, Schultz M, et al. Endocrine parameters and alpha-tocopherol therapy of patients with mammary dysplasia. Cancer Res 1981;41:3811-3.

13. Ernster VL, Goodson WH, Hunt TK, et al. Vitamin E and benign breast “disease”: a double-blind, randomized clinical trial. Surgery 1985;97:490-4.

14. London RS, Sundaram GS, Murphy L, et al. The effect of vitamin E on mammary dysplasia: a double-blind study. Obstet Gynecol 1985;65:104-6.

15. Marshall JM, Graham S, Swanson M. Caffeine consumption and benign breast disease: a case-control comparison. Am J Publ Health 1982;72(6):610-2.

16. Lubin F, Ron E, Wax Y, et al. A case-control study of caffeine and methylxanthines in benign breast disease. JAMA 1985;253(16):2388-92.

17. Boyle CA, Berkowitz GS, LiVoisi VA, et al. Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study. J Natl Cancer Inst 1984;72:1015-9.

18. Vecchia C, Franceschi S, Parazzini F, et al. Benign breast disease and consumption of beverages containing methylxanthines. J Natl Cancer Inst 1985;74:995-1000.

19. Ernster VL, Mason L, Goodson WH, et al. Effects of a caffeine-free diet on benign breast disease: a randomized trial. Surgery 1982;91:263.

20. Allen S, Froberg DG. The effect of decreased caffeine consumption on benign proliferative breast disease: a randomized clinical trial. Surgery 1987;101:720-30.

21. Minton JP, Foecking MK, Webster DJT, Matthew RH. Caffeine, cyclic nucleotides, and breast disease. Surgery 1979;86:105-8.

22. Minton JP, Abou-Issa H, Reiches N, et al. Clinical and biochemical studies on methylxanthine-related fibrocystic breast disease. Surgery 1981;90:299-304.

23. Rose DP, Boyar AP, Cohen C, Strong LE. Effect of a low-fat diet on hormone levels in women with cystic breast disease. I. Serum steroids and gonadotropins. J Natl Cancer Inst 1987;78:623-6.

24. Woods MN, Gorbach S, Longcope C, et al. Low-fat, high-fiber diet and serum estrone sulfate in premenopausal women. Am J Clin Nutr 1989;49:1179-83.

25. Rose DP, Boyar A, Haley N, et al. Low fat diet in fibrocystic disease of the breast with cyclic mastalgia: a feasibility study. Am J Clin Nutr 1985;41(4):856 [abstract].

26. Boyd NF, McGuire V, Shannon P, et al. Effect of a low-fat high-carbohydrate diet on symptoms of cyclical mastopathy. Lancet 1988;ii:128-32.

27. Lubin F, Wax Y, Ron E, et al. Nutritional factors associated with benign breast disease etiology: a case-control study. Am J Clin Nutr 1989;50:551-6.

28. Prior JC, Vigna Y, Sciarretta D, et al. Conditioning exercise decreases premenstrual symptoms: a prospective, controlled 6-month trial. Fertil Steril 1987;47(3):402-8.

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.

Drugs used to treat FIBROCYSTIC BREAST DISEASE. Select drug name to view medication information and pricing