Cluster-Headache Explained

Cluster Headache

Chili Peppers
Capsaicin, a constituent of cayenne pepper, applied inside the nostrils may ease the pain of cluster headaches and reduce recurrences.
Dose:
Consult a qualified healthcare practitioner
Chili Peppers
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Substance P is a nerve chemical involved in pain transmission that may cause some of the symptoms of cluster headache.²^,3 Capsaicin, a constituent of cayenne pepper, can reduce the levels of substance P in nerves.⁴ Preliminary clinical trials investigating the use of intranasal capsaicin for the prevention and treatment of cluster headaches report significant decreases in the number of cluster episodes in some of the participants.⁵ The decreases usually lasted no more than 40 days after the end of treatment,⁶ although a few patients have experienced relief for up to two years.⁷ In a double-blind study, patients who received capsaicin intranasally twice daily for seven days during a cluster episode had a significant reduction in pain for the following 15 days.⁸ As capsaicin can cause burning and irritation, this treatment should be utilized only under the supervision of a qualified doctor.
Melatonin
Taking melatonin before bedtime has been shown to reduce the frequency of cluster headaches.
Dose:
Take under medical supervision: 10 mg daily in the evening
Melatonin
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Researchers have found low levels of the hormone melatonin in cluster headache patients.⁹^,10^,11^,12 In a small double-blind trial, a group of cluster headache sufferers took a 10 mg evening dose of melatonin for 14 days. About half of the group saw a significant decrease in the frequency of their headaches within three to five days, after which no further headaches occurred until melatonin was discontinued.¹³ Melatonin appears to be effective against both types of cluster headache (e.g., episodic and chronic). ¹⁴ More research is needed to establish the long-term effects of melatonin supplementation on cluster headache.
Boswellia
In case reports, several patients with chronic cluster headaches showed improvement after supplementing with Boswellia serrata extract, though more research is needed to confirm these findings.
Dose:
Refer to label instructions
Boswellia
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In case reports, four patients with chronic cluster headaches showed improvement after supplementing with Boswellia serrata extract.^[REF] The amount used varied from 350 mg three times per day to 700 mg three times per day. Placebo-controlled trials are needed to confirm these reports.
Magnesium
People who suffer from cluster headaches often have low blood levels of magnesium, magnesium injections have been shown to bring relief.
Dose:
Refer to label instructions
Magnesium
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People who suffer from cluster headaches often have low blood levels of magnesium, and preliminary trials¹⁵^,16 show that intravenous magnesium injections may relieve a cluster headache episode. However, no trials have investigated the effects of oral magnesium supplementation on cluster headaches.

Holistic Options

Oxygen therapy has been found to be useful in treating cluster headaches. A double-blind trial compared breathing 100% oxygen with breathing air (nitrogen and oxygen) through a mask for 15 minutes or less during six headache episodes per person. The 100% oxygen significantly reduced the pain of acute cluster attacks in all subjects.¹⁷ A controlled trial found that during acute episodes of cluster headaches, breathing 100% oxygen through a mask for 15 minutes significantly decreased pain in most of the people with episodic cluster headache and in over half of those with chronic cluster headache.¹⁸ However, one-fourth of the study participants experienced cluster attacks soon after the treatment was stopped. While oxygen inhalation therapy is now considered a standard treatment,¹⁹ treatments may need to be repeated, and they have not been shown to help prevent recurrences.

In controlled studies,²⁰^,21 a single treatment of hyperbaric oxygen therapy, in which the patient is placed in a chamber with highly concentrated oxygen, has been found to help decrease pain and prevent recurrence of cluster episodes in some patients for several days. Two studies have investigated the use of multiple treatments of hyperbaric oxygen in chronic cluster headache patients. In one small, preliminary trial,²² ten 70-minute treatments over two weeks brought relief in most of the participants; headaches did not recur for 1 to 31 days after the end of treatment in those who responded. In another preliminary trial, chronic cluster headache patients received 15 hyperbaric oxygen treatment sessions (every other day for 30 minutes each); results showed a gradual decrease in episodes in some patients, which lasted for up to two weeks after treatment ended.²³

Cluster Headache

Health Condition