Peginterferon alfa-2b
Pronounced
"peg-in-ter-FEER-on alfa"
Uses
Peginterferon alfa-2b is used alone or in combination with ribavirin to treat chronic hepatitis C, a viral infection of the liver. It works by decreasing the amount of hepatitis virus in the body and helps your body's natural defense (immune system) fight the infection. If untreated, chronic hepatitis infection can lead to serious liver damage (cirrhosis) and liver cancer.
It is not known if peginterferon can cure hepatitis C infection or can prevent you from passing the virus to others. Practice "safer sex" (such as the use of latex condoms) to lower the risk of passing the virus to others.
Warning
This medication may rarely cause or worsen some serious medical conditions, including mental/mood problems (such as depression), autoimmune conditions (such as lupus, rheumatoid arthritis), blood vessel problems (such as heart disease), or infections. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you develop any serious symptoms or side effects (see Side Effects section). Some side effects may go away or lessen after stopping treatment with this medication.
This medication is often used in combination with ribavirin. Ribavirin may cause birth defects and/or death to an unborn baby. Women must avoid pregnancy while they or their male partners are using ribavirin. Also, ribavirin may cause a blood disorder (hemolytic anemia), which can worsen heart disease. If you are using peginterferon alfa-2b with ribavirin to treat chronic hepatitis C, also carefully read the drug information for ribavirin.
How to Use This Medication
Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using peginterferon alfa-2b and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. To increase comfort, remove this medication from the refrigerator and let it warm to room temperature as directed in the Instructions for Use. Do not warm up this medication in any other way such as heating in the microwave or placing in hot water. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Inject this medication under the skin in your thigh or stomach as directed by your doctor, usually once weekly. Some brands may also be injected in the outer surface of your upper arm. Do not inject near the belly button or at the waistline. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not shake this medication. Doing so may make it work less well.
The dosage is based on your medical condition, weight, lab tests, and response to treatment. In children, the dosage is also based on body size. Use this medication regularly to get the most benefit from it. To help you remember, use it at about the same time on the same day each week.
Drink plenty of fluids while using this medication unless your doctor directs you otherwise.