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AMIFOSTINE (am i FOS teen) reduces the risk of kidney injury caused by cisplatin, a type of chemotherapy. It may also be used to help decrease dryness in the mouth caused by radiation to the head or neck.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is injected into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Medications for blood pressure
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Your condition will be monitored carefully while you are receiving this medication.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication. Your care team can help you find the option that works for you.
Do not breast-feed while taking this medication.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
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This does not apply.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Low calcium level—muscle pain or cramps, confusion, tingling, or numbness in the hands or feet
-Rash, fever, and swollen lymph nodes
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Seizures
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Diarrhea
-Fatigue
-Flushing
-Hiccups
-Nausea
-Sneezing
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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