• Image of Cotellic medication Image of Cotellic medication
    • COTELLIC

    • QTY 45
    • 20 MG
    • Tablet
    • Near  98144

COBIMETINIB (KOE bi ME ti nib) treats skin cancer. It may also be used to treat blood and bone marrow cancers. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.


COTELLIC Lifestyle Interactions

  • Cobimetinib 20mg, Oral tablet

    Interaction: Grapefruit juice
    Severity: Major
    Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.
    Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during cobimetinib treatment due to the risk for increased cobimetinib exposure and adverse reactions. Cobimetinib is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.