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ARTEMETHER; LUMEFANTRINE (ar TEM e ther; loo me FAN treen) treats malaria. It works by killing the parasite that causes malaria. It will not treat colds, the flu, or infections caused by bacteria or viruses.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with food or a milky drink. Take it as directed on the prescription label at the same time every day. Swallow the tablets whole. You may crush the tablet and mix it with 1 to 2 teaspoons of water in a clean container. Swallow the medication and water right away. If you vomit within 1 hour after taking your dose, take your dose again. If you vomit the second dose, tell your care team. Take all the medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.
Do not take this medication with grapefruit juice.
Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 2 months for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Cisapride
-Dronedarone
-Lumacaftor; ivacaftor
-Pimozide
-Some antivirals for HIV, such as saquinavir
-Some medications for cancer, such as apalutamide, encorafenib, enzalutamide, mitotane
-Some medications for fungal infections, such as fluconazole, ketoconazole, posaconazole
-Some medications for seizures, such as carbamazepine or phenytoin
-Some medications for tuberculosis, such as rifampin or rifapentine
-St. John's wort
-Thioridazine
This medication may also interact with the following:
-Estrogen or progestin hormones
-Grapefruit and foods or drinks that contain grapefruit
-Other medications that cause heart rhythm changes
-Some other medications for malaria, such as mefloquine or quinine
This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. Tell your care team if you get flu-like symptoms (chills, fever, muscle pains, or headaches) again after you have finished all of your medication.
Estrogen and progestin hormones may not work as well while you are taking this medication. If you are using these hormones for contraception, talk to your care team about using a second type of contraception. A barrier contraceptive, such as a condom or diaphragm, is recommended.
Tell your care team if you vomited any of your doses or if you are not able to eat.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Dizziness
-Headache
-Joint pain
-Loss of appetite
-Muscle pain
-Unusual weakness or fatigue
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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