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PAROXETINE (pa ROX e teen) reduces the number and severity of hot flashes due to menopause. It belongs to a group of medications called SSRIs.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth once daily at bedtime. Follow the directions on the prescription label. This medication can be taken with or without food. Take your medication at regular intervals. Do not take your medication more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Linezolid
-MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
-Methylene blue (injected into a vein)
-Pimozide
-Thioridazine
This medication may also interact with the following:
-Alcohol
-Amphetamines
-Aspirin and aspirin-like medications
-Atomoxetine
-Certain medications for irregular heart beat, such as propafenone, flecainide, encainide, and quinidine
-Certain medications for mental health conditions
-Certain medications for migraine headache, such as almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
-Cimetidine
-Digoxin
-Diuretics
-Fentanyl
-Fosamprenavir
-Furazolidone
-Isoniazid
-Lithium
-Medications that treat or prevent blood clots, such as warfarin, enoxaparin, and dalteparin
-Medications for sleep
-NSAIDs, medications for pain and inflammation, such as ibuprofen or naproxen
-Phenobarbital
-Phenytoin
-Procarbazine
-Rasagiline
-Ritonavir
-Supplements, such as St. John's wort, kava kava, valerian
-Tamoxifen
-Tramadol
-Tryptophan
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
This medication may worsen depression and cause thoughts of suicide. This can happen at any time but is more common after first starting treatment and after a change in dose. Talk to your care team right away if you have changes in mood and behavior or thoughts of self-harm or suicide. They can help you.
This medication may increase your risk of bone fractures. Tell your care team if you have pain, swelling, or trouble moving a part of your body like you usually can.
Talk to your care team if you become pregnant while taking this medication.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Irritability, confusion, fast or irregular heartbeat, muscle stiffness, twitching muscles, sweating, high fever, seizure, chills, vomiting, diarrhea, which may be signs of serotonin syndrome
-Low sodium level—muscle weakness, fatigue, dizziness, headache, confusion
-Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
-Thoughts of suicide or self-harm, worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Change in sex drive or performance
-Diarrhea
-Excessive sweating
-Nausea
-Tremors or shaking
-Upset stomach
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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