JANUMET XR
  • JANUMET XR

  • QTY 60 • 50-1000 MG • TBMP 24HR • Near 77381

METFORMIN; SITAGLIPTIN (met FOR min; sit a GLIP tin) is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.

JANUMET XR Lifestyle Interactions

Sitagliptin Phosphate 50mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

Tobacco

· Severity: Moderate

· Notes for Consumers: If you use tobacco or are trying to quit tobacco use, monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase blood sugar. Also, if you are trying to quit tobacco use, as your body adjusts, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and talk with your health care provider if they occur. Monitor your blood sugar regularly.

· Notes for Professionals: Tobacco smoking is known to aggravate insulin resistance. The cessation of tobacco smoking may result in a decrease in blood glucose. Blood glucose concentrations should be monitored more closely whenever a change in either smoking status occurs; dosage adjustments in antidiabetic agents may be needed.

Sitagliptin Phosphate 50mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

Alcohol

· Severity: Moderate

· Notes for Consumers: It is best to limit the ingestion of alcohol during use of this medicine. Alcohol can increase the risk for severe or prolonged low blood sugar. If you do choose to drink alcohol, make sure you do not take it on an empty stomach. Frequently monitor your blood sugar. Know the signs and symptoms of low blood sugar and how to treat them. Do not drive or operate machinery or perform other hazardous tasks while ingesting alcohol.

· Notes for Professionals: Patients should be advised to limit alcohol ingestion when treated with an antidiabetic agent. Alcohol inhibits gluconeogenesis, which can contribute to or increase the risk for hypoglycemia. In some patients, hypoglycemia can be prolonged. If a patient with diabetes ingests alcohol, they should be counselled to to avoid ingestion of alcohol on an empty stomach, which increases risk for low blood sugar. Patients should also be aware of the carbohydrate intake provided by certain types of alcohol in the diet, which can contribute to poor glycemic control. If a patient chooses to ingest alcohol, they should monitor their blood glucose frequently. Many non-prescription drug products may be formulated with alcohol; instruct patients to scrutinize product labels prior to consumption.

Sitagliptin Phosphate 50mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

Tobacco

· Severity: Mild

· Notes for Consumers: If you use tobacco or are trying to quit tobacco use, you may need to monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase the blood sugar. Also, if you are trying to quit smoking, as your body adjusts to not smoking, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and report them if they occur. Monitor your blood sugar regularly.

· Notes for Professionals: Tobacco smoking is known to aggravate insulin resistance. The cessation of tobacco smoking may result in a decrease in blood glucose. Blood glucose concentrations should be monitored more closely whenever a change in either smoking status occurs; dosage adjustments in antidiabetic agents may be needed.

Sitagliptin Phosphate 50mg, Metformin Hydrochloride 1,000mg, Oral tablet, extended release

Alcohol

· Severity: Moderate

· Notes for Consumers: Avoid or limit the use of alcohol with metformin, due to an increased risk for side effects. Avoid excessive use of alcohol in any form. Alcohol-containing beverages can increase the risk of low blood sugar or can cause increased blood sugar due to the calories in these beverages. Limit alcohol containing medicines and beverages if you are a patient with diabetes. If you use a blood sugar monitoring device, check your blood sugar regularly. Learn the signs and symptoms of high or low blood sugar and know how you should treat these if they occur. Contact your health care provider immediately if you experience extreme weakness, increasing drowsiness, or difficulty breathing (heavy breathing, shortness of breath) which are symptoms of the more serious side effects of Metformin.

· Notes for Professionals: Patients taking metformin should be advised to limit their use of alcohol. Blood lactate concentrations and the lactate to pyruvate ratio are increased during excessive (acute or chronic) intake of alcohol with metformin. Elevated lactic acid concentrations are associated with increased morbidity rates as the risk for lactic acidosis is increased. In patients with diabetes, alcohol intake can also cause hypoglycemia or worsen glycemic control as it provides a source of additional calories. Many non-prescription drug products may be formulated with alcohol; have patients scrutinize product labels prior to consumption.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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