DOXEPIN HCL
  • DOXEPIN HCL (Generic for PRUDOXIN)

  • QTY 30 • 10 MG • Capsule • Near 77381

DOXEPIN/Sinequan (DOX e pin) treats depression and anxiety. It increases the amount of serotonin and norepinephrine in the brain, hormones that help regulate mood. It belongs to a group of medications called tricyclic antidepressants (TCAs).

DOXEPIN HCL (Generic for PRUDOXIN) Lifestyle Interactions

Doxepin Hydrochloride 10mg, Oral capsule

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause confusion, dizziness, lightheadedness, and increased risk of falling. Call emergency services right away if you experience slow or shallow breathing, difficulty staying awake, or are unable to respond or wake up.

· Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants such as tricyclic antidepressants (TCAs). TCAs may exaggerate the CNS depressant response to alcohol, leading to an increase in sedation or psychomotor impairment. In some studies, alcohol has increased the unbound form of the TCA in the blood, which might be related to exaggerated clinical effect.

Doxepin Hydrochloride 10mg, Oral capsule

Tobacco

· Severity: Moderate

· Notes for Consumers: Tobacco smoking may reduce the effectiveness of this drug in treating your condition. The smoke contains substances that speed the removal of this drug from the body. If you take this drug and are trying to quit smoking, you may experience increased drug-related side effects like drowsiness, constipation, dizziness, difficulty with urination, dry mouth and eyes or confusion if you stop smoking. Make sure your prescriber is aware if you smoke or if you are trying to quit smoking.

· Notes for Professionals: Physiological changes resulting from tobacco smoking cessation, with or without nicotine replacement, may alter the pharmacokinetics of certain concomitant medications, such as tricyclic antidepressants (TCAs). Doses of TCAs may need to be adjusted in patients who successfully quit smoking. Tobacco smoking has been shown to increase the clearance of TCAs by inducing hepatic microsomal enzymes, likely due to the hydrocarbons of tobacco smoke. Sudden smoking cessation may result in a reduced clearance of TCAs, despite the initiation of nicotine replacement products.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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