ARIPIPRAZOLE
  • ARIPIPRAZOLE

  • (Generic for ABILIFY)
  • QTY 30 • 5 MG • Tablet • Near 77381

ARIPIPRAZOLE (ay ri PIP ray zole) is an atypical antipsychotic. It is used to treat schizophrenia and bipolar disorder, also known as manic-depression. It is also used to treat Tourette's disorder and some symptoms of autism. This medicine may also be used in combination with antidepressants to treat major depressive disorder.

ARIPIPRAZOLE Lifestyle Interactions

Aripiprazole 5mg, Oral tablet

Marijuana

· Severity: Major

· Notes for Consumers: Avoid this combination. It may cause your condition to get worse. Marijuana may also decrease the efficacy of this medicine, making it not work as well for you. Do not drive or operate machinery until you know how this combination will affect you. Contact your health care provider right away if you notice unusual changes in moods or behaviors of any type.

· Notes for Professionals: It is recommended that patients avoid the use of marijuana, by any route, if they are treated for a psychiatric history, including psychosis and bipolar disorder, as the cannabinoids (the psychoactive ingredients, such as THC) in marijuana can produce psychotoxic effects and may exacerbate psychiatric disorders. A high frequency of use and use of products with high-potency of THC are potential risk factors for psychiatric effects. Additive CNS effects, such as sedation or CNS depression are also possible. Clinical studies suggest that cannabis use may reduce the efficacy of some antipsychotic drugs. In addition, several cannabinoids in marijuana appear to influence the activity of CYP enzymes and P-glycoprotein, which may alter the concentrations of antipsychotics and influence either safety or efficacy.

Aripiprazole 5mg, Oral tablet

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: Tell your health care provider if you drink grapefruit juice regularly. An interaction between Aripiprazole and Grapefruit juice is possible, but they may be used together. Grapefruit juice may change the amount of Aripiprazole in the blood. If you drink Grapefruit juice regularly, do not change how often or how much grapefruit juice you drink until you talk to your health care provider. If you experience nausea, vomiting, drowsiness, tremor or other unusual effect, contact your health care provider.

· Notes for Professionals: Grapefruit and grapefruit juice inhibit CYP3A4 metabolism in gut enterocytes, and therefore may decrease aripiprazole metabolism, resulting in increased blood concentrations of aripiprazole. Patients should not significantly adjust their intake of grapefruit or grapefruit juice while taking aripiprazole. As with drugs that significantly inhibit the CYP3A4 pathway, consideration should be given to altering the aripiprazole dose.

Aripiprazole 5mg, Oral tablet

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause confusion, dizziness, lightheadedness, and increased risk of falling. Call emergency services right away if you experience slow or shallow breathing, difficulty staying awake, or are unable to respond or wake up.

· Notes for Professionals: Advise patients to avoid alcohol consumption while taking CNS depressants. Alcohol consumption may result in additive CNS depression.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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