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SOFOSBUVIR; VELPATASVIR; VOXILAPREVIR (soe FOS bue veer; vel PAT us veer; VOX eh la pre veer) treats infections caused by the hepatitis C virus. It works by limiting the spread of the virus inside the body. It is a combination of three antiviral medications. It will not treat colds, the flu, or infections caused by bacteria.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a full glass of water. Take it as directed on the prescription label at the same time every day. Take it with food. Keep taking it unless your care team tells you to stop.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Rifampin
This medication may also interact with the following:
-Amiodarone
-Antacids
-Certain antibiotics, such as rifabutin, rifapentine
-Certain medications for cholesterol, such as atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin
-Certain medications for diabetes
-Certain medication for HIV and AIDS, such as atazanavir, efavirenz, lopinavir; ritonavir, tenofovir, tipranavir
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin
-Certain medications for stomach problems, such as cimetidine, famotidine, omeprazole, lansoprazole
-Cyclosporine
-Dabigatran
-Digoxin
-Imatinib
-Irinotecan
-Lapatinib
-Methotrexate
-Mitoxantrone
-Sulfasalazine
-St. John's wort
-Topotecan
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. You will need to have bloodwork done while taking this medication.
If you have had hepatitis B infection (HBV) in the past, taking this medication could cause the HBV to become active again. If you have had HBV, your care team should monitor you with blood tests. Tell your care team right away if you develop a general ill feeling, light-colored stools, loss of appetite, unusual weakness, or yellowing of the eyes or skin.
This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Diarrhea
-Dizziness
-Fatigue
-Headache
-Nausea
-Trouble sleeping
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, pour the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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