POMALIDOMIDE (pom a LID oh mide) treats multiple myeloma, a type of bone marrow cancer. It may also be used to treat Kaposi sarcoma, a cancer that often causes lesions on the skin or inside the mouth. It works by slowing down the growth of cancer cells.

POMALIDOMIDE (Generic for POMALYST) Lifestyle Interactions

  • Pomalidomide 4mg, Oral capsule

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take grapefruit juice without talking to your health care professional. Avoid grapefruit juice during pomalidomide treatment if possible. Taking pomalidomide with grapefruit juice may increase the levels of pomalidomide in your body, especially if you are taking certain other medicines. This may increase the risk for side effects such as low blood cell counts, increased risk of bleeding, fatigue, constipation / diarrhea, and nausea.
    • Notes for Professionals: Pomalidomide is a substrate of CYP1A2, CYP3A, and P-glycoprotein (P-gp). Grapefruit juice is an inhibitor of P-gp. Avoid concomitant use of pomalidomide and grapefruit juice, particularly in combination with both a strong CYP1A2 and a strong CYP3A4 inhibitor. If coadministration of pomalidomide with grapefruit juice and these CYP inhibitors cannot be avoided, decrease the dose of pomalidomide to 2 mg once daily and monitor for efficacy and toxicity. If pomalidomide is co-administered with grapefruit juice in the absence of both a CYP1A2 and CYP3A4 inhibitor, monitor closely for pomalidomide toxicity.

  • Pomalidomide 4mg, Oral capsule

    • Interaction: Tobacco
    • Severity: Major
    • Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
    • Notes for Professionals: Advise patients to avoid smoking tobacco while taking pomalidomide. Smoking tobacco has been observed to decrease pomalidomide exposure by approximately 32% and may decrease efficacy.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.