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    • LISRAYA

BREPOCITINIB (BREP oh SYE ti nib) treats dermatomyositis, an autoimmune condition that causes muscle weakness and skin rash. It works by slowing down an overactive immune system. This decreases symptoms.


LISRAYA Lifestyle Interactions

  • Brepocitinib 30mg, Oral tablet

    • Interaction: Tobacco
    • Severity: Major
    • Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
    • Notes for Professionals: Advise patients to avoid smoking tobacco while taking brepocitinib. Smoking tobacco may reduce brepocitinib overall exposure and efficacy. Smoking tobacco induces CYP1A2 and brepocitinib is a CYP1A2 substrate. Brepocitinib overall exposure was observed to be an estimated 45% lower in current smokers compared to non-smokers.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.