LINEZOLID (Generic for ZYVOX)

Linezolid 600mg, Oral tablet

Alcohol

· Severity: Major

· Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication increases the risk for serious side effects. Contact your care team if you experience new or worsening side effects.

· Notes for Professionals: Advise patients to avoid beverages with a high tyramine content, such as some red wines, while taking linezolid. A significant pressor response has been observed in normal adult subjects receiving linezolid and tyramine doses of more than 100 mg.

Linezolid 600mg, Oral tablet

Caffeine-containing Foods/Beverages

· Severity: Moderate

· Notes for Consumers: Try to limit caffeine intake while taking Linezolid. Side effects from Linezolid may get worse if you take Caffeine, like increased blood pressure, confusion, restlessness, or other side effects. All preparations containing caffeine should be used sparingly such as tea, coffee, chocolate, cola, or 'stay awake' products. Some nonprescription medicines also contain caffeine and should not be taken along with Linezolid.

· Notes for Professionals: Linezolid is an antibiotic that is also a reversible, non-selective inhibitor of MAO. Dangerous cardiac arrhythmias or severe hypertension can occur because of the potentiation of caffeine's sympathomimetic effects by MAOIs. Caffeine use should be minimized or avoided during and for 1 to 2 weeks after discontinuation of any MAOI.

Linezolid 600mg, Oral tablet

Tyramine-containing foods

· Severity: Major

· Notes for Consumers: Certain foods containing tyramine might increase the risk of side effects with Linezolid. You should probably limit your intake of alcoholic beverages, aged or smoked meats (like sausages or smoked or pickled fish), aged cheeses, and caffeine containing foods like coffee, colas, teas, and chocolate while on Linezolid. Taking these foods along with Linezolid might increase the risk of increased blood pressure, confusion, restlessness, or other side effects. Ask your dietician or health care professional for a complete listing of foods best avoided while on Linezolid.

· Notes for Professionals: Linezolid is an antibiotic that is also a reversible, non-selective inhibitor of MAO. Foods containing tyramine should be avoided.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>