LIDOCAINE-PHENYLEPHRINE-WATER Lifestyle Interactions

  • Phenylephrine Hydrochloride 15mg/1mL, Lidocaine Hydrochloride 10mg/1mL, Intraocular solution

    • Interaction: Cannabis
    • Severity: Major
    • Notes for Consumers: Discuss cannabis use with your care team. The effects of your medication may be altered if used with cannabis.
    • Notes for Professionals: Advise patients to avoid cannabis use during lidocaine treatment due to decreased exposure of lidocaine which may alter its efficacy. Cannabis use induces CYP1A2 and lidocaine is a CYP1A2 substrate. The induction potential of cannabis is greatest with chronic inhalation. Other routes of administration or sporadic use may have less of an effect.

  • Phenylephrine Hydrochloride 15mg/1mL, Lidocaine Hydrochloride 10mg/1mL, Intraocular solution

    • Interaction: Caffeine-containing Foods/Beverages
    • Severity: Moderate
    • Notes for Consumers: Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Phenylephrine. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Phenylephrine may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.
    • Notes for Professionals: Caffeine is a CNS-stimulant and such actions are expected to be additive when coadministered with other CNS stimulants or psychostimulants.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.