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FINERENONE (fin ER e none) lowers the risk of worsening kidney disease in people with type 2 diabetes. It may also lower the risk of heart attack, worsening heart failure, and death caused by kidney disease in people with type 2 diabetes. It can also be used to lower the risk of worsening disease and death caused by heart failure. It works by blocking the effect of the hormone aldosterone in your body. This decreases inflammation and injury in the kidneys, heart, and blood vessels.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Swallow the tablets whole. You may crush the tablet and put the contents in a small amount of water or soft foods such as applesauce. Swallow the medication mixture right away. Keep taking it unless your care team tells you to stop.
Do not take this medication with grapefruit or grapefruit juice.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Adagrasib
-Ceritinib
-Certain antivirals for HIV or hepatitis, such as atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir
-Certain medications for fungal infections, such as itraconazole, ketoconazole, posaconazole, or voriconazole
-Chloramphenicol
-Clarithromycin
-Grapefruit and grapefruit juice
-Idelalisib
-Lonafarnib
-Mifepristone
-Nefazodone
-Ribociclib
-Telithromycin
-Tucatinib
This medication may also interact with the following:
-Amiodarone
-Certain diuretics, such as amiloride, spironolactone, triamterene
-Certain medications for high blood pressure, such as enalapril, candesartan, lisinopril, valsartan
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin
-Efavirenz
-Erythromycin
-Potassium salts or supplements
-Rifampin
-St. John's wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. You may need blood work done while you are taking this medication.
Avoid salt substitutes unless you are told otherwise by your care team.
Talk to your care team before breast-feeding. Changes to your treatment plan may be needed.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-High potassium level—muscle weakness, fast or irregular heartbeat
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put into the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.