TOREMIFENE CITRATE
  • TOREMIFENE CITRATE

  • (Generic for FARESTON)
  • QTY 30 • 60 MG • Tablet • Near 77381

TOREMIFENE (tore EM i feen) blocks the effects of estrogen. It is used to treat some types of breast cancer.

TOREMIFENE CITRATE Lifestyle Interactions

Toremifene Citrate 60mg, Oral tablet

Grapefruit juice

· Severity: Major

· Notes for Consumers: Do not eat or drink grapefruit or grapefruit juice while taking Toremifene without talking to your doctor or healthcare professional. Grapefruit can increase the amount of Toremifene in your blood which can increase the risk of a dangerous change in heartbeat or heart rhythm. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat).

· Notes for Professionals: Instruct patients to avoid grapefruit juice while receiving toremifene due to increased plasma concentrations of toremifene which may result in QT prolongation. Toremifene is a CYP3A4 substrate that has been shown to prolong the QTc interval in a dose- and concentration-related manner, and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor increased toremifene exposure by 2.9-fold; exposure to N-demethyltoremifene was reduced by 20%.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

DISCLAIMER: This content is provided for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.

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