• Image of Esbriet medication Image of Esbriet medication
    • PIRFENIDONE (Generic for ESBRIET)

    • QTY 90
    • 267 MG
    • Capsule
    • Near  77381

PIRFENIDONE (peer FEH nih done) treats pulmonary fibrosis, a condition that causes the lungs to scar and stiffen, making it hard to breathe. It works by preventing changes to the lung tissue. This delays worsening symptoms.


PIRFENIDONE (Generic for ESBRIET) Lifestyle Interactions

  • Pirfenidone 267mg, Oral capsule

    Interaction: Tobacco
    Severity: Major
    Notes for Consumers: Do not smoke or use tobacco products while taking this medication. When used together, your medication may not work as well for you.
    Notes for Professionals: Advise patients to avoid smoking tobacco while taking pirfenidone. Smoking tobacco may reduce pirfenidone overall exposure and efficacy. Smoking tobacco induces CYP1A2 and pirfenidone is a CYP1A2 substrate. Smoking has been observed to decrease pirfenidone peak and overall exposure by 68% and 46%, respectively.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.