EPLERENONE
  • EPLERENONE

  • (Generic for INSPRA)
  • QTY 30 • 25 MG • Tablet • Near 77381

EPLERENONE (e PLER en one) is used to treat high blood pressure. This medicine is also used to improve symptoms of heart failure.

EPLERENONE Lifestyle Interactions

Eplerenone 25mg, Oral tablet

Grapefruit juice

· Severity: Severe

· Notes for Consumers: Do not take these drugs together. Discuss possible alternative treatment options with your prescriber. Taking these drugs together can increase the amount of Eplerenone in your blood and may cause your blood pressure to be too low or increase the amount of potassium in your blood. When there is too much potassium in the blood it can cause muscle weakness or an abnormal heart rhythm.

· Notes for Professionals: Concomitant use of grapefruit or grapefruit juice and eplerenone is contraindicated. Grapefruit potently inhibits the hepatic CYP3A4 isoenzyme and may increase serum eplerenone concentrations by about 25% and, hence, can increase the risk of developing eplerenone-induced hyperkalemia and hypotension.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

DISCLAIMER: This content is provided for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.

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