DASATINIB (da SA ti nib) treats leukemia. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

DASATINIB (Generic for SPRYCEL) Lifestyle Interactions

  • Dasatinib 50mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take Dasatinib with grapefruit or grapefruit juice. Taking Dasatinib with grapefruit or grapefruit juice may increase side effects of Dasatinib. If you accidentally take Dasatinib with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.
    • Notes for Professionals: Instruct patients to avoid grapefruit or grapefruit juice with dasatinib due to the potential for increased dasatinib exposure and subsequent toxicity. Dasatinib is sensitive CYP3A4 substrate and grapefruit is a strong CYP3A4 inhibitor. Coadministration of another strong CYP3A4 inhibitor increased the mean Cmax and AUC of dasatinib by 4-fold and 5-fold, respectively.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.