XANOMELINE; TROSPIUM (zan OH mah line; TROSE pee um) treats schizophrenia. It works by balancing the level of substances in your brain that help regulate mood, behavior, and thoughts. It belongs to a group of medications called antipsychotics. Antipsychotic medications can be used to treat several kinds of mental health conditions.

COBENFY Lifestyle Interactions

  • Xanomeline 100mg, Trospium Chloride 20mg, Oral capsule

    • Interaction: Alcohol
    • Severity: Major
    • Notes for Consumers: Do not drink alcohol while taking this medication. Drinking alcohol while taking this medication can cause serious side effects, such as central nervous system (CNS) depression, and can increase the risk of falling. Call emergency services right away if you experience symptoms of CNS depression: slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake.
    • Notes for Professionals: Advise patients to avoid alcohol and alcohol-containing products while taking trospium. Alcohol consumption may result in additive CNS depression. Alcohol should not be consumed within 2 hours of trospium extended-release capsules.

  • Xanomeline 100mg, Trospium Chloride 20mg, Oral capsule

    • Interaction: Caffeine-containing Foods/Beverages
    • Severity: Mild
    • Notes for Consumers: The intake of beverages containing caffeine may decrease the actions of trospium because caffeine may increase urination. You may wish to limit your caffeine intake (including intake of coffee, colas, teas, or herbal supplements) while taking trospium.
    • Notes for Professionals: Consuming > 400 mg/day caffeine has been associated with the development of urinary incontinence. Caffeine may aggravate bladder symptoms and counteract the effectiveness of drugs used to treat overactive bladder, like trospium, to some degree. Patients with overactive bladder may wish to limit their intake of caffeine including caffeine from drugs, dietary supplements (i.e., guarana), beverages (i.e., teas, coffee, colas), or foods (i.e., chocolate).

  • Xanomeline 100mg, Trospium Chloride 20mg, Oral capsule

    • Interaction: High Fat Foods
    • Severity: Moderate
    • Notes for Consumers: Food may decrease the amount of trospium absorbed by the stomach, which can decrease the effects of trospium. To limit this interaction, take trospium on an empty stomach, at least one hour before meals.
    • Notes for Professionals: Trospium is minimally absorbed after oral administration (< 10%). Administration with food (a high fat meal) significantly reduces absorption. Patients should be advised to take trospium at least 1 hour before meals on an empty stomach.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.