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ADAPT BARRIER Lifestyle Interactions
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Vanzacaftor 10mg, Tezacaftor 50mg, Deutivacaftor 125mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.• Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during vanzacaftor; tezacaftor; deutivacaftor treatment due to the risk of increased vanzacaftor; tezacaftor; deutivacaftor exposure and adverse reactions. Vanzacaftor; tezacaftor; deutivacaftor is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
