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ACT DRY MOUTH Lifestyle Interactions
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Darifenacin 15mg, Oral tablet, extended release
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not drink grapefruit juice or eat grapefruit while taking this medication. Grapefruit may alter the effects of your medication. Serious side effects may occur. Contact your care team right away if you experience new or worsening side effects.• Notes for Professionals: Advise patients to avoid grapefruit and grapefruit juice during darifenacin treatment due to the risk for increased darifenacin exposure and adverse reactions. Darifenacin is a CYP3A substrate and grapefruit juice is a CYP3A inhibitor. -
Darifenacin 15mg, Oral tablet, extended release
• Interaction: Caffeine-containing Foods/Beverages• Severity: Mild• Notes for Consumers: The intake of beverages containing caffeine may decrease the actions of Darifenacin because Caffeine may increase urination. You may wish to limit your caffeine intake (including intake of coffee, colas, teas, or herbal supplements) while taking Darifenacin.• Notes for Professionals: Consuming > 400 mg/day caffeine has been associated with the development of urinary incontinence. Caffeine may aggravate bladder symptoms and counteract the effectiveness of darifenacin to some degree. Patients may wish to limit their intake of caffeinated drugs, dietary supplements (e.g., guarana), or beverages (e.g., green tea, other teas, coffee, colas).
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
